these blog posts are written by Dr. alfredo G. Tomasselli, a Retired bio-Chemist and Bio-physicist who spent his life in Academia and The Pharmaceutical Industry researching cures and treatments for diseases such as HIV/Aids, Diabetes, and Rheumatoid arthritis. His daughter sara inspires this blog and helps to write posts. sara was diagnosed with type 1 diabetes on april 4th, 2014 at the age of 30. 

2015 FreeStyle Libre Flash Glucose Monitoring System, already in use in Europe

The ability to continuously monitor blood glucose concentration 24/7 and keep a computerized record of months of measurements would be invaluable for disease management, especially if the equipment involved is non-cumbersome to carry, relatively pain free, and reliable in determining glucose concentration, and not in need of routine finger prick calibrations. Such a monitor, would avoid annoying multi pricks per day, determine possible blood glucose’s excessive highs and lows especially during the night, and would tell if treatment and lifestyle are alright. Several CGM’s are already on the market (e.g, Dexcom G4 Platinum, Medtronic Enlite® Sensor, and FreeStyle Navigator II), but I haven’t tried any yet. Presently, I am following a new generation of CGM from Abbott, specifically the Abbott FreeStyle® FreeStyle® Libre Flash Glucose Monitoring System that has received the European Community approval for marketing in September 2014 and is already available to patients in seven European countries (it is not approved in the USA). It is a flash glucose monitoring system, so not exactly continuous glucose monitoring and measures glucose in the intercellular fluid, rather than in the blood as the usual finger prick system does. This system was brought to my attention at the beginning of this year by a teenager named Ester, who lives in Spain and became a relative after I married her cousin. Ironically, months after I met her at my wedding, both of us were diagnosed with Type 1 Diabetes.  Esther has told me that she knows people who use FreeStyle® Libre and are very enthusiastic about it. The system is described in the Abbott Diabetes Care page (https://www.abbottdiabetescare.com/press-room/2014/2014-e.html ) and there are good comments about it from several users, e.g.,   http://missjengrieves.com/2014/09/15/freestyle-libre-review-a-gamechanger-for-diabetes-management/  and http://diatribe.org/latest-european-experiences-abbott-groundbreaking-freestyle-libre-system.  Its main features are a sensor about the size of a 2 euro coin connected to a filament inserted in the interstitial fluid under the patient’s skin. This system is placed in the back of the upper arm of the patient for up to 14 days; which at this point would need to be replaced. The sensor reads the glucose concentration every minute, plots the glucose concentration average every 15 minutes, and stores graphically the readings occurred over a span of eight hours. Moreover, the patient can take readings any time he/she would like to; the procedure is simple and consists of swiping a reader over the sensor and in a second both a real-time and an 8-hour glucose history are obtained. Other features include: the reader holds up to 90 days of data. No finger prick calibrations are needed. It will tell you if glucose is going up or down. Readings can be taken even when the sensor is covered by clothing.

 

2015 Artificial Pancreas: an interesting publication

2015 Update: Stem Cell educator technology (Interpreted comments by Dr's Jesus Otero & Elias Delgado who led the Spanish Trials)